bookmark_borderReversing memory/cognitive impairment with medicinal plants targeting inflammation and its crosstalk with other pathologies


Table 1

Table 4

3.6. Individual plant species demonstrate multiple anti- neuroinflammatory mechanisms

Gypenosides (from Gynostemma pentaphyllum) reduced levels of brain proinflammatory mediators IL-1β, IL-6 and NF-κB, and reduced LPS-induced elevated levels of TLR4 mRNA

Jiaogulan Extrakt

Jiaogulan Extrakt
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bookmark_borderNeuroprotection Induced by Artemisia, Ginseng, Astragalus and Ginkgo for the Therapy of Alzheimer’s Disease



Astragaloside IV (AS-IV), a small molecular saponin purified from Astragalus membranaceus , is the main active ingredient and is well-known for its multiple peripheral pharmacological effects and central nervous system neuroprotective effects, with evidences in animal models indicating its therapeutic potential for AD and Parkinson’s disease.

AS-IV can improve behavioral and neurochemical deficits largely due to its antioxidant, antiapoptotic and anti-inflammatory properties.

AS-IV enhances stroke patients’ recovery from their neurological disability and improves functional outcome.

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